5 Defenders® is a certified organic mushroom extract complex from Real Mushrooms, available as a bulk powder. The formula combines five functional mushroom extracts: Organic Turkey Tail (Trametes versicolor) mushroom extract, Organic Reishi (Ganoderma lingzhi) mushroom extract, Organic Maitake (Grifola frondosa) mushroom extract, Organic Shiitake (Lentinula edodes) mushroom extract, and Organic Chaga (Inonotus obliquus) extract. The blend is optimized to contain more than 18% beta-(1,3)(1,6)-glucans, polysaccharides that support the body's normal immune response.

All mushroom extracts are sourced through Nammex, a supplier with more than 40 years of mushroom growing experience and one of the first companies to bring organic functional mushroom extracts to North America. Mushrooms are organically grown or wildcrafted from mountain regions and are grown using Di Dao (地道) cultivation practices — a philosophy of harvesting in geo-authentic environments. Extracts are produced using hot water extraction to unlock the full spectrum of beneficial compounds. Every batch is tested twice for heavy metals, agricultural chemicals, and microbial contamination to meet dietary supplement standards.

The five extract powders are present in fixed proportions: 30% Turkey Tail, 20% Reishi, 20% Shiitake, 20% Maitake, and 10% Chaga. The product contains no grain, starch, or fillers. It is suited to daily wellness routines and is designed to be blended into coffee, tea, smoothies, or other beverages.

5 Defenders® holds USDA Certified Organic status through Quality Assurance International and has received the Purity-IQ Authenticity Certification, which uses nuclear magnetic resonance to confirm correct mushroom species identity. The product is produced in a GMP-compliant facility. It has been rated the best mushroom supplement brand by ConsumerLab.com survey respondents for five consecutive years.