Genestra Scorbatate 6 oz (170 grams)
Genestra Scorbatate- 6 oz (170 grams)
• High-potency Vitamin C formulation • 1,000 mg per serving • With added minerals • Ideal for vegans • Convenient powder format increases patient compliance
Scorbatate provides a high concentration of vitamin C in a buffered mineral base formula to help in the development and maintenance of bones, cartilage, teeth and gums; helps the body to metabolize fats and proteins; helps in wound healing and connective tissue formation; an antioxidant for the maintenance of good health; helps to prevent vitamin C deficiency; provides support for healthy glucose metabolism and helps to maintain healthy skin, immune and proper muscle function (1).
References: 1. NHPD Monograph on Multi-vitamin and mineral. October 2007.
Additional product info: Aging is accompanied by a variety of physiological, psychological, economic and social changes that compromise nutritional status and/or affect nutritional requirements. For these reasons, the diets of many older adults do not currently meet the recommended intake levels of several essential vitamins and minerals; thus, low micronutrient status is often reported in this population. Nutritional status surveys of the elderly indicate a low to moderate prevalence of frank nutrient deficiencies, but an increased risk of malnutrition, along with evidence of subclinical deficiencies having a direct impact on physiologic function. Overt micronutrient deficiencies have been reported as prevalent in nursing home populations, and recommendations were made that all institutionalized older adults receive a multivitamin/mineral supplement for general nutritional prophylaxis. A clinical study has shown that multivitamin treatment for 8 weeks significantly increased, compared to placebo, plasma concentrations of vitamins D, E, pyridoxal phosphate, folate, B12, C, and improved the riboflavin activity coefficient. Supplementation with a multivitamin formulated at about 100% Daily Value can thus decrease the prevalence of suboptimal vitamin status in older adults and improve their micronutrient status to levels associated with reduced risk for several chronic diseases (2). Oxidative stress also plays an important role in the pathogenesis of cardiovascular disease (CVD). Growing evidence suggest that antioxidant vitamins such as Vitamin E and Vitamin C might reduce the risk of disease outcomes by their ability to scavenge free radicals. A case-control study with vitamin E (400 IU/d) and vitamin C (500 mg/d) supplementation in 40 CVD patients for 2 mo showed reduced lipid peroxidation and a strengthened antioxidant defense system. Hence, vitamin E and vitamin C supplementation may have beneficial effects on the heart by reducing oxidative stress in CVD patients (3). The NHPD recommendations for zinc supplementation in adults to help maintain healthy skin are between 0.7-50 mg per day (4).
Adequate zinc status is critical for immune function. Zinc deficiency reduces generation of T cells, depresses humoral and cell-mediated immunity, leads to lymphopenia and thymic atrophy, and increases the frequency and number of infections (5). A prospective, randomized, controlled clinical trial was conducted involving 231 HIV-infected adults with low plasma zinc levels, who were randomly assigned to receive zinc (12 mg of elemental zinc for women and 15 mg for men) or placebo for 18 months. Zinc supplementation given to HIV-infected adults resulted in a 4-fold decrease in the likelihood of immunological failure, defined as a decrease of CD4+ cell count to <200 cells/mm3, after 18 months of use, compared with placebo. Zinc supplementation also significantly reduced diarrhea, compared with placebo (6). Chromium (Cr) is an essential element required for normal carbohydrate and lipid metabolism. Signs of Cr deficiency have been documented on numerous occasions, including elevated blood glucose, insulin, cholesterol and triglycerides, and decreased high density lipoproteins (HDL) in humans consuming normal diets. A review reports that the response to Cr supplementation for glucose, insulin, lipids, and related variables is related to the amount and form of supplemental Cr, the degree of glucose intolerance, and the duration of the study. Subjects with glucose intolerance but not diabetes usually respond to 200 µg of Cr daily as Cr chloride or other more bioavailable forms of Cr (7). The NHPD recommendations for chromium supplementation in adults to provide support for healthy glucose metabolism are between 2.2-500 µg per day (8).
Attributes of Scorbatate covered by the NHPD Monograph on Multivitamin and Mineral are: Vitamin C and Selenium are antioxidants for the maintenance of good health. Magnesium helps to maintain proper muscle function. Magnesium, Manganese and Zinc help the body to metabolize carbohydrates, fats and proteins. Vitamin C helps the body to metabolize fats and proteins. Molybdenum helps the body to metabolize proteins. Chromium helps the body to metabolize carbohydrates and fats. Vitamin C helps in wound healing (9).
References: 2. McKay DL, Perrone G, Rasmussen H, Dallal G, Hartman W, Cao G, Prior RL, Roubenoff R, Blumberg JB. The effects of a multivitamin/mineral supplement on micronutrient status, antioxidant capacity and cytokine production in healthy older adults consuming a fortified diet. J Am Coll Nutr. 2000 Oct;19(5):613-21. Abstract; Page 613, Introduction; Page 616, Water-Soluble Vitamins, 1st paragraph 3. Karajibani M, Hashemi M, Montazerifar F, Dikshit M. Effect of vitamin E and C supplements on antioxidant defense system in cardiovascular disease patients in Zahedan, southeast Iran. J Nutr Sci Vitaminol (Tokyo). 2010;56(6):436-40. Abstract; Page 436, Introduction, 1st paragraph; Page 439, Conclusion 4. NHPD Monograph on Multivitamin and Mineral. October 2007. 5. Baum MK, Lai S, Sales S, Page JB, Campa A. Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults. Clin Infect Dis. 2010 Jun 15;50(12):1653-60. Abstract; Page 1653, 1st paragraph;Page 1657, Discussion, 1st paragraph; Page 1658, Conclusion 6. Baum MK, Lai S, Sales S, Page JB, Campa A. Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults. Clin Infect Dis. 2010 Jun 15;50(12):1653-60. Abstract; Page 1653, 1st paragraph;Page 1657, Discussion, 1st paragraph; Page 1658, Conclusion 7. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr. 1998 Dec;17(6):548-55. Page 548, Introduction, 1st paragraph; Page 553, Summary, 1st paragaph 8. NHPD Monograph on Chromium (from non-picolinate sources). December 2009. 9. NHPD Monograph on Multivitamin and Mineral. October 2007.
Other ingredients: Silica, citric acid