Genestra Pumpkin 90 capsules
Genestra Pumpkin Capsules- 60 caps
• Pumpkin seed oil in capsule format • Source of linoleic acid, oleic acid, palmitic acid and stearic acid • Convenient softgel format • Increases patient compliance
Pumpkin Capsules provides pumpkin seed oil as a source of essential fatty acids for the maintenance of good health (1).
References: 1 EMA Monograph on Cucurbita pepo L. September 2011.
Additional product info: Benign prostatic hyperplasia (BPH) is a pathological symptom frequently found in the elderly population. The use of complementary and alternative medicine (CAM) for the treatment of BPH patients has a long history, especially in European countries (2). Pumpkin seed oil (1-4 grams) have been traditionally used in Herbal Medicine for the relief of lower urinary tract symptoms related to benign prostatic hyperplasia or related to an overactive bladder (3). A randomized, double-blind, placebo-controlled trial was performed over 12 months on 47 benign prostatic hyperplasia patients with average age of 53.3 years and international prostate symptom score over 8. Subjects received either sweet potato starch (group A, placebo, 320 mg/day), pumpkin seed oil (group B, 320 mg/day), saw palmetto oil (group C, 320 mg/day) or pumpkin seed oil plus saw palmetto oil (group D, each 320 mg/day). In groups B, C and D, the international prostate symptom score were reduced by 3 months. Quality of life score was improved after 6 months in group D, while those of groups B and C were improved after 3 months, compared to the baseline value. Maximal urinary flow rate were gradually improved in groups B and C, with statistical significance after 6 months in group B and after 12 months in group C. Based on the results of this study, it could be suggested that pumpkin seed oil and saw palmetto oil are clinically safe and may be effective complementary and alternative medicine for BPH (4).
Pumpkin seed oil is rich in phytoestrogens and animal studies suggest that there is some benefit to supplementation in low estrogen conditions. A randomized, double-blind, placebo-controlled pilot study was performed and included 35 women who had undergone natural menopause or had iatrogenically entered the climacteric due to surgery for benign pathology. Wheat germ oil (placebo; n = 14) and pumpkin seed oil (n = 21) were administered to eligible participants over a 12-week period at a dose of 2 g per day. Women receiving pumpkin seed oil showed a significant increase in high density lipoprotein cholesterol concentrations. There was also a significant improvement in the menopausal symptom scores, with a decrease in severity of hot flushes, less headaches and less joint pains being the main contributors.
This pilot study showed pumpkin seed oil had some benefits for postmenopausal women (5).
References: 2 Hong H, Kim CS, Maeng S. Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutr Res Pract. 2009 Winter;3(4):323-7. 3 EMA Monograph on Cucurbita pepo L. September 2011. 4 Hong H, Kim CS, Maeng S. Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutr Res Pract. 2009 Winter;3(4):323-7. 5 Gossell-Williams M, Hyde C, Hunter T, Simms-Stewart D, Fletcher H, McGrowder D, Walters CA. Improvement in HDL cholesterol in postmenopausal women supplemented with pumpkin seed oil: pilot study. Climacteric. 2011 Oct;14(5):558-64. Abstract