Genestra Femagen PMS 90 tablets

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Genestra Femagen PMS Tablets- 90 tabs


• Multivitamin, mineral, glandular and botanical formulation • With dong quai, wild yam and blue cohosh • Helps to relieve symptoms associated with premenstrual syndrome • Helps normal growth • Helps in tissue formation • Helps to form red blood cells and helps in their proper function • Helps to maintain proper muscle function • Convenient tablet format • Increases patient compliance

Femagen Tablets combines vitamins, minerals, glandular tissues and synergistic herbs in a convenient tablet format.

Additional product info: Beta-carotene at 65-3,000 mcg RAE per day is a source of Vitamin A to help maintain eyesight, skin, membranes and immune function (1).

Scientific evidence suggests that cyclic fluctuations in a variety of nutrients, especially calcium, may help to explain some features of premenstrual syndrome (PMS). A double-blind clinical study determined the efficacy of calcium supplementation in women suffering from PMS. The subjects were divided in two groups; one group received placebo and the other received 500 mg of calcium carbonate twice daily for 3 months. The results showed that calcium supplements reduced early fatigability and changes in appetite in women with PMS (2). Seventy-eight women were initially screened to participate in another randomized, double-blind crossover trial, to determine the efficacy of calcium supplementation in women with PMS. Trial selection was based on a history of recurrent PMS symptoms and on the results of a prospective assessment of daily symptom scores. Each participant received six months of treatment involving three months of tablets containing 1000 mg of elemental calcium per day in form of calcium carbonate and three months of placebo. Multivariate repeated measures analysis of variance on symptom ratings derived from daily PMS symptom scores demonstrated a reduction in symptoms on calcium treatment during both the luteal and the menstrual phases of the reproductive cycle. Retrospective assessment of overall symptoms confirmed this reduction: 73% of the women reported fewer symptoms during the treatment phase on calcium. Premenstrual factors (negative affect and pain) and one menstrual factor (pain) were significantly alleviated by calcium (3).

The objective of a study was to determine the effect of magnesium (Mg), combination of vitamin B6 and Mg, and the placebo on the severity of PMS. The participants were randomly assigned to two intervention groups and one control group. To confirm the PMS diagnosis in patients, they were asked to fill out the PMS daily symptom record form for two months and then, when the diagnosis was confirmed, the participants were randomly assigned to one of the three groups of the study (250 mg Mg daily, 250 mg Mg plus 40 mg vitamin B6 daily, and placebo). Medical intervention was carried out in two menstrual cycles and the results of pre- and post-test were compared. The findings indicated that Mg plus vitamin B6 and placebo has the greatest and the least effect on the mean score of PMS, respectively (4).

Results of a study indicate that iron deficiency without anemia impairs favorable adaptation to aerobic exercise in iron-depleted, nonanemic women. In the study, forty-two iron-depleted, nonanemic women (18–33 yr old) received 100 mg of ferrous sulfate (S) (20 mg elemental iron) or placebo (P) per day for 6 weeks in a randomized, double-blind trial. Iron supplementation increased serum ferritin and decreased transferrin receptors in the S compared with the P group. The S and P groups decreased 15-km time and respiratory exchange ratio and increased work rate during the 15-km time trial after training. The decrease in 15-km time was greater in the S than in the P group and could be partially attributed to increases in serum ferritin and Hb (5). Non-anaemic women with unexplained fatigue may benefit from iron supplementation as shown in a clinical study when oral ferrous sulphate (80 mg/day of elemental iron) was ingested daily for four weeks (6). Iron at 1.4 to 45 mg per day helps to form red blood cells and helps in their proper function (7).

References: 1 NHPD Monograph on Multi-Vitamin and Mineral. October 2007. 2 Ghanbari Z, Haghollahi F, Shariat M, Foroshani AR, Ashrafi M. Effects of calcium supplement therapy in women with premenstrual syndrome. Taiwan J Obstet Gynecol. 2009 Jun;48(2):124-9. Abstract 3 Thys-Jacobs S, Ceccarelli S, Bierman A, Weisman H, Cohen MA, Alvir J. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med. 1989 May-Jun;4(3):183-9. Abstract 4 Fathizadeh N, Ebrahimi E, Valiani M, Tavakoli N, Yar MH. Evaluating the effect of magnesium and magnesium plus vitamin B6 supplement on the severity of premenstrual syndrome. Iran J Nurs Midwifery Res. 2010 Dec;15(Suppl 1):401-5. 5 Hinton PS, Giordano C, Brownlie T, Haas JD. Iron supplementation improves endurance after training in iron-depleted, nonanemic women. J Appl Physiol. 2000 Mar;88(3):1103-11. Abstract 6 Verdon F, Burnand B, Stubi CL, Bonard C, Graff M, Michaud A, Bischoff T, de Vevey M, Studer JP, Herzig L, Chapuis C, Tissot J, Pécoud A, Favrat B. Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. BMJ. 2003 May 24;326(7399):1124. Abstract 7 NHPD Monograph on Multi-vitamin and Mineral. October 2007.